Italy’s highest court on Thursday confirmed a slander conviction against U.S. defendant Amanda Knox for accusing an innocent man of murdering her British flatmate 17 years ago in a sensational case that polarized trial watchers on both sides of the Atlantic.

Italy’s high court has upheld the remaining conviction against American Amanda Knox, who was jailed and later acquitted of the 2007 murder of her British roommate Meredith Kercher.