First responders are searching for more victims after at least nine people died and 11 were injured when a UPS plane crashed while taking off from the airport in Louisville, Kentucky. The plane crashed Tuesday as it was departing for Honolulu from Louisville’s Muhammad Ali International Airport.

LOCATION AND SCALEThe Worldport facility in Louisville Muhammad Ali International Airport spans about 5.2 million square feet, or roughly 90 football fields and serves as the global air logistics nerve center for UPS. Handles around 2 million packages per day. The automated sorting system can process up to 420,000 packages/letters per hour.

LOUISVILLE, Ky. -- A UPS cargo plane crashed and exploded in a massive fireball Tuesday while taking off from the company’s global aviation hub in Louisville, Kentucky, killing at least seven people and injuring 11, authorities said.

As the sun set and businesses started to close in Louisville, Kentucky, on Tuesday, the evening calm was suddenly shattered by a giant explosion near the city’s airport.

A UPS cargo flight 2976 crashed around 5:15 ET after it took off from Louisville Muhammad Ali International Airport, Kentucky, en route to Honolulu, Secretary of the US Department of Transportation Sean Duffy said. The aircraft was a McDonnell Douglas MD-11.

Louisville airport officials join mayor Craig Greenberg to provide updates after a plane crashed near Louisville Muhammad Ali International Airport