Layoffs have begun at the Department of Health and Human Services, including at the Food and Drug Administration and the Centers for Disease Control and Prevention.

After weeks of White House hype and public anxiety, President Trump is set Wednesday to announce a barrage of self-described “reciprocal” tariffs on friend and foe alike. The new tariffs — coming on what Trump has called “Liberation Day” — is a bid to boost US manufacturing and punish other countries for what he has said are years of unfair trade practices.