The melanoma differentiation-associated gene-7 (mda-7), cloned from a human melanoma cell line H0–1, is known to induce tumor cell-selective growth inhibition in breast cancer cells in vitro and loss ...

Preclinical data for VCN-12, the next candidate from Theriva’s VCN-X discovery program, highlight a novel mechanism of action ...

The latest update is out from Candel Therapeutics ( (CADL) ).

CAN-2409 is the lead product candidate from the adenovirus platform. The Company recently completed a pivotal, placebo-controlled, phase 3 clinical trial of CAN-2409 in localized prostate cancer, ...

Viral vectors dominate gene therapy, with lentivirus, adenovirus, and AAV being key players, each with unique advantages and limitations. Non-viral vectors, such as lipid nanoparticles and GalNAc, ...

VCN-01 expanded mPDAC data from VIRAGE Phase 2b trial to be presented at ESMO 2025 -- SYN-004 Interim blinded safety and pharmacokinetic data ...

The modified common cold viruses behind high-profile COVID-19 vaccine candidates from China's CanSino Biologics and Russia's Gamaleya Institute have been studied for decades, but are still not widely ...