Please provide your email address to receive an email when new articles are posted on . Kim’s hypothesis arises partially from studies that showed that C3, when introduced to synthetic neutrophils, ...

Activation of the alternative pathway of the complement system has been implicated in the pathogenesis of age-related macular degeneration. Membrane attack complex (MAC) has been identified mainly on ...

BOSTON (July 22, 2015) - Vision researchers at Massachusetts Eye and Ear/Harvard Medical School (HMS) Department of Ophthalmology have taken a first step in solving a vexing problem: how to preserve ...

Omeros Corporation (Nasdaq: OMER) today announced the closing of the asset sale and licensing transaction between Omeros and Novo Nordisk for the candidate drug zaltenibart (formerly OMS906).

Three research groups investigating the genetics of age-related macular degeneration (AMD) from different angles independently report evidence that a chronic, low-level immune attack in the retina ...

Phase I Clinical Trial in healthy subjects shows that NM3086 was safe and well tolerated at all doses (0.1 to 20 mg/kg) in six cohorts. Total AP inhibition was achieved through all cohorts and the ...

RESEARCH TRIANGLE PARK, N.C., Aug. 26, 2022 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that its oral Factor D inhibitor, BCX9930, demonstrated >99 percent ...

Left untreated, PNH could cause death in about half of patients within 10 years of diagnosis. The primary cause of PNH-related mortality is thromboembolic events. A host of anti-complement strategies, ...

J. S. Spika, P. K. Peterson, B. J. Wilkinson, D. E. Hammerschmidt, H. A. Verbrugh, J. Verhoef, P. G. Quie The Journal of Infectious Diseases, Vol. 146, No. 2 (Aug ...

The lesions of Stx-related hemolytic–uremic syndrome, which are indistinguishable from those of its atypical form on the basis of standard histologic analysis, are characterized by thickening of ...