Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare disease characterized by progressive surfactant accumulation and hypoxemia caused by autoantibodies against granulocyte–macrophage ...

Researchers at Texas Biomedical Research Institute report they have created a new cell culture model for human alveolar macrophages in the lab. The model was developed to improve research for lung ...

Researchers have discovered that lung-based immune cells can be "trained" to remember a previously encountered pathogen, making them more efficient at clearing out the cellular debris that accumulates ...

In a recent study, investigators from Rockefeller University and other institutions have discovered a never-before-documented genetic disorder that causes the improper functioning of macrophages. The ...

Exposure alters immune cell movement and reduces pathogen clearance, increasing the risk of severe lung infections. Study: Alveolar macrophage function is impaired following inhalation of berry ...

BIRMINGHAM, Ala. – Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages — the white blood cells that defend the body by killing microbes, ...