Researchers have discovered how the protein CodY controls toxin production of Clostridium difficile, a bacterium that has caused epidemics of severe diarrhea in hospital patients. In its search for ...

Clostridiodes difficile infection has become a leading cause of severe, sometimes fatal diarrheal illness. It flourishes best in hospitals and long-term care facilities where people are on long-term ...

A new study, led by researchers from the University of California, Irvine (UCI), uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating ...

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile ("C. diff") -- the leading cause of hospital-acquired ...

Researchers from the University of Maryland School of Medicine and their colleagues have identified the structure of the most lethal toxin produced by certain strains of Clostridium difficile bacteria ...

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C. diff infections are triggered by two toxins the bacterium produces. Both toxins are difficult to block and prior investigations from the same clinical team have revealed the nature of how they ...

Clostridium difficile, or C. diff— a potentially deadly bacterial infection that’s gained attention due to its treatment by fecal transplants— occurs when the body’s natural balance of gut bacteria ...

In a hamster model of Clostridium difficile, infection with C. difficile strains producing either toxin A or toxin B caused fulminant disease, according to a research team from the University of ...

BOSTON, May 19, 2014 /PRNewswire/ -- Sanofi Pasteur, the vaccines division of Sanofi , presented Phase II trial (H-030-012) results for an investigational vaccine for the prevention of Clostridium ...

Clostridiodes difficile infection has become a leading cause of severe, sometimes fatal diarrheal illness, with the bacterium's toxins causing the damage. New work cements our knowledge of how C. diff ...

BOSTON (Sept. 5, 2007) — As if being admitted to the hospital weren’t bad enough, patients, once admitted, are at higher risk of becoming infected with a “superbug” bacterium, Clostridium difficile (C ...