A handful of people with HIV have been cured after receiving HIV-resistant stem cells – but a man who received non-resistant ...
For the seventh time on record, a patient with both HIV and cancer has had the virus eliminated from their body. As in most ...
A German man remains in remission from HIV an incredible six years after he received a stem cell transplant to treat an ...
Human immunodeficiency virus (HIV) infection is a viral infection that causes acquired immunodeficiency syndrome (AIDS) by gradually destroying certain leukocytes. When HIV enters the human body, it ...
T-cell expression levels of CC chemokine receptor 5 (CCR5) are a critical determinant of HIV/AIDS susceptibility, and manifest wide variations (i) between T-cell subsets and among individuals and (ii) ...
Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that its collaborators at the University of Pennsylvania have opened a Phase 1 clinical trial to evaluate SB-728-T for the treatment of ...
Scientists are closer than ever to a functional HIV cure. This World AIDS Day, an expert breaks down what's real, what's hype ...
Purpose: The mechanism of action, pharmacology, pharmacokinetics, clinical efficacy, drug interactions, adverse effects, dosage and administration, cost, and role in therapy of maraviroc are reviewed.
Certain chemokines act as natural antagonists of human immunodeficiency virus (HIV) by blocking key viral coreceptors, such as CCR5 and CXCR4, on the surface of susceptible cells. Elucidating the ...
December 20, 2010 — Replacing host stem cells with donor-derived cells homozygous for the CCR5 gene variant Δ32 (CCR5Δ32/Δ32) resulted in the HIV viral reservoir being reduced over time, strongly ...
We have recently reported that the mean number of CCR5 coreceptors at the surface of CD4+ T cells (CCR5 density) correlates with viral load and disease progression in HIV-1-infected persons. Here, we ...