Chronic and viral infections can literally exhaust certain key cells in the immune system from a constant barrage of attacks.

Aging is known to be a risk factor for the biological changes that create the dangerous buildup of plaque in arteries called atherosclerosis, and aging also induces a buildup of memory CD8 T cells, a ...

If biology did have a motto, it may well be ‘nothing is ever as simple as it seems,’ an idea which is exemplified by today’s scientific story. It comes to us from the Prlic Lab in the Vaccine and ...

The ability of immune cells-particularly CD8 + T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies. However, the factors and ...

A study in the journal Science Immunology now shows how two subsets of one type of immune cell — the CD8 T cell — develop to provide either short-term or long-term immune protection. The study focuses ...

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...