Beijing Zhongke Journal Publising Co. Ltd. Congenital heart defects (CHDs) are the most common birth defects, occurring in approximately 0.9% of live births. Sadly, they are also the leading cause of ...

Atrial septal defect (ASD) is a hole in the wall between the heart’s two upper chambers. ASD is a congenital heart defect, meaning it is present from birth. In some cases of ASD, a small hole may only ...

The same molecular pathway that is responsible for preventing adult heart cells from regenerating after being damaged - like after a heart attack - has been identified as involved in embryonic ...

An atrial septal defect is an opening or hole in the wall that sits between the heart’s two upper chambers. The heart’s upper chambers are called the right and left atria. Some people refer to atrial ...

Fibroblasts are an essential component of the heart, as they play key roles in its structure, development and response to ...

An ostium primum atrial septal defect (ASD) occurs when then atrial septum near the atrioventricular valves has a communication between the two atrium causing a left to right shunt. This rarely ...

A broad spectrum of procedures ranging from basic diagnostic cardiac catheterization to transcatheter closure of atrial septal defects (ASDs) has progressed to the point where such techniques are ...

New Approach Methodologies (NAMs) are revolutionizing disease modeling with human-based models that enhance predictive accuracy. iPSC-derived cardiac organoids lead this innovation, offering insights ...

Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is limited by the shortcomings of existing experimental models. Traditional ...

An atrial septal defect of the secundum type is relatively common and occurs from failure of the septum secundum to develop. This results in a communication between the left and right atrium directly ...

An atrial septal defect is a congenital heart issue. According to the Centers for Disease Control and Prevention (CDC), it develops in about 1 in 1,859 babies in the United States. An atrial septal ...