Chinese hamster ovary (CHO) cells are the most widely used cells for producing biopharmaceuticals. Engineering gene expression in CHO is key to improving drug quality and affordability. However, ...

We have engineered two Chinese hamster ovary cell lines secreting different recombinant glycoproteins to express high levels of human β1,4-galactosyltransferase (GT, E.C. 2.4.1.38) and/or ...

Biological drugs, as well as animal testing, concern both consumers and researchers. But, as these drugs can save or extend lives, they provide important advances in medicine. I have always loved ...

Chinese Hamster Ovary cells also referred to as “CHO cells,” have a long history of being used as research tools. Since their introduction to biomedical research in the 1950s, these cells have become ...

China has officially approved its fifth and latest COVID-19 vaccine. And it has one special ingredient, The New York Times reports: ovary cells from hamsters. The vaccine itself was co-developed by ...

Peck-Sun Lin, Stephanie Quamo, Kwei-Chi Ho and Kenneth Baur A metal chelator, diethyldithiocarbamate (DDC) perturbs the chromosome condensation processes in dividing cells. The length of the metaphase ...

A homologous series of uncharged nitroxyl biradicals have been examined as hypoxic cell sensitizers. In the series piperidinic nitroxyl moieties were separated by alkane-dicarboxamide bridging groups ...