A new research paper titled "Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes" has been published in Aging. Senescent cells (SnCs) have been described to accumulate ...

Articular chondrocytes in joints affected by osteoarthritis (OA) have a senescent phenotype that is induced by gradual accumulation of genomic DNA damage, according to new research published in ...

ACI and MACI treatments could be improvised with the first of its kind feat by Edogawa Hospital, Tokyo TOKYO--(BUSINESS WIRE)--Regenerative therapy to treat knee joint damages gets a boost with a ...

A new research paper titled "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes" has been published in Aging. While advanced age is widely ...

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA). However, the ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into ...

Researchers have generated photosynthetic mammalian cells by transplanting essential components of plant-derived chloroplasts into chondrocytes. When transplanted into degenerating chondrocytes in ...

(A) UMAP visualization of the 13,363 chondrocytes from healthy human cartilage. Color represents the chondrocyte subset. (B) UMAP visualization of the expression of representative marker genes for ...

The growth plate is divided into several distinct regions, each populated with cartilage cells (chondrocytes) displaying characteristic behaviors. Nearest the heads of the bone is a germinal zone ...

BUFFALO, NY-September 20, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, ...