Stay up to date here with the latest news and highlights from the Indianapolis Colts' Week 16 matchup on Monday Night ...

USA TODAY's NFL experts make their picks for a Week 16 showdown between the Indianapolis Colts and San Francisco 49ers.

It's always a terrific thing when the punter is never called upon. That is exactly what happened to the San Francisco 49ers ...

In order for the Colts to come away with a much-needed win, here are three keys to accomplishing that. The Colts' downfield ...

The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy ’s career-high ...

San Francisco cornerback Deommodore Lenoir was fined Saturday by the NFL after his unnecessary roughness penalty in Monday's ...

Monday Night Football in Week 16 features a battle between two playoff hopefuls in the San Francisco 49ers and Indianapolis ...

The 49ers dealt a devastating blow to the Colts' playoff hopes on Monday night and there was plenty of blame to go around in ...

CB Deommodore Lenoir was fined $11,593 for unnecessary roughness (late hit) on Colts RB Jonathan Taylor. Here’s what happened ...

A Sunday NFL Week 17 slate provides another chance to claim the latest DraftKings promo code, which gives new users $200 in ...