Caldwell et al [38] are credited with the initial study suggesting that NAFLD may account for a large percentage of otherwise cryptogenic cirrhosis based on clinical parameters related to NAFLD.

Clinicians should, therefore, be aware of the potential role of endocrine disorders in patients with cryptogenic liver disease and of the effects of liver function on the endocrine system.

A specific mutation of keratin 8 (G61C) was found to be a genetic risk factor for the development of cryptogenic liver cirrhosis. The purpose of the present paper was therefore to determine the ...