Tiffany Gholar’s studio in the Fine Arts Building is a riot of color—magentas, oranges, yellows, and greens detail cabinets, surfaces, and windowpanes. Even her outfit complements the room’s palette.

Though Los Angeles interior designer Amy Sklar makes a business of creating—er—human-scaled design, when we tapped her to participate in Season 2 of Dollhouse Beautiful, it wasn’t her first brush with ...