Please provide your email address to receive an email when new articles are posted on . In patients with moderate to severe eosinophilic asthma, treatment with dexpramipexole depleted blood and tissue ...

Elevated absolute eosinophil counts and absolute basophil counts (ABC) are associated with reduced overall survival in essential thrombocythemia. In polycythemia vera, higher ABC correlates with ...

Dupilumab (interleukin-4Rα; antibody binds to interleukin-4Rα, inhibiting interleukin-4 and interleukin-13 signaling in hematopoietic cells [e.g., B cells, CD4+ helper T cells, and eosinophils], ...

PITTSBURGH--(BUSINESS WIRE)--Knopp Biosciences LLC today reported further clinical and biomarker data demonstrating that reduction in eosinophil count by oral dexpramipexole significantly correlated ...

Among adults with moderate to severe asthma receiving rademikibart, those with a high eosinophil count plus high fractional ...

Eosinophils are a type of white blood cell. Low eosinophil numbers may occur due to certain medications or an underlying health condition, such as Cushing syndrome. Eosinophils play a role in the ...

The phase 3 EXHALE-4 study demonstrated that dexpramipexole, an oral small molecule therapy, significantly improved ...

PITTSBURGH--(BUSINESS WIRE)--Knopp Biosciences LLC today announced detailed results of its positive Phase 2 dose-ranging EXHALE trial of the novel oral eosinophil-lowering drug dexpramipexole in ...

In the EXHALE-4 study, dexpramipexole met the primary endpoint with statistically significant improvement in lung function compared with placebo Dexpramipexole demonstrated statistically significant ...