Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...
Breast cancer imaging has evolved into a vital tool in personalised oncology, particularly in the evaluation of estrogen receptor (ER) dynamics. Modern imaging techniques, notably positron emission ...
A new Salk Institute study suggests that estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue. Across the body, tiny bean-shaped structures called mitochondria ...
University of Florence–led investigators report that estrogen-regulated renal progenitor cells shape pregnancy adaptation in mice with failure of estrogen receptor alpha signaling precipitating ...
A study led by researchers at the Fujita Health University School of Medicine, in collaboration with Chiba University's Graduate School of Medicine and Fukuoka University, Japan, revealed that ...
Announcing a new publication for Acta Materia Medica journal. Endocrine therapy that blocks estrogen receptor signaling has been effective for decades as a primary treatment choice for breast cancer ...
Estrogen receptor positive (ER+) metastatic breast cancer (MBC) is an incurable condition affecting approximately 168,000 women annually in the US. Fulvestrant, an Estrogen Receptor Degrader, is a ...
VERITAC-2 trial shows vepdegestrant improves progression-free survival in ESR1-mutant breast cancer, marking a clinical milestone for PROTAC therapy. The trial did not reach statistical significance ...
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