Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...
Breast cancer imaging has evolved into a vital tool in personalised oncology, particularly in the evaluation of estrogen receptor (ER) dynamics. Modern imaging techniques, notably positron emission ...
A new Salk Institute study suggests that estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue. Across the body, tiny bean-shaped structures called mitochondria ...
A study led by researchers at the Fujita Health University School of Medicine, in collaboration with Chiba University's Graduate School of Medicine and Fukuoka University, Japan, revealed that ...
University of Florence–led investigators report that estrogen-regulated renal progenitor cells shape pregnancy adaptation in mice with failure of estrogen receptor alpha signaling precipitating ...
Announcing a new publication for Acta Materia Medica journal. Endocrine therapy that blocks estrogen receptor signaling has been effective for decades as a primary treatment choice for breast cancer ...
Estrogen receptor positive (ER+) metastatic breast cancer (MBC) is an incurable condition affecting approximately 168,000 women annually in the US. Fulvestrant, an Estrogen Receptor Degrader, is a ...
VERITAC-2 trial shows vepdegestrant improves progression-free survival in ESR1-mutant breast cancer, marking a clinical milestone for PROTAC therapy. The trial did not reach statistical significance ...
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