Bile acids (BAs) are traditionally ... Gut secrets FGF15/19 that can activate hepatic FGFR4 and its downstream signaling cascade, leading to repressed hepatic BA biosynthesis. However, ...

Background: Fibroblast Growth Factor Receptor 4 (FGFR4) is the fourth member of a family of FGF tyrosine kinase receptors that regulate cellular pathways involved in proliferation, differentiation and ...

Research led by the Department of General and Visceral Surgery, Faculty of Medicine, University of Freiburg, Germany has ...

India, April 20 -- Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti ...

One of the hallmarks of UC is a deficiency in certain bile acids, molecules that help digest fats and regulate gut health.

Bile acids, which are altered by bacteria normally living in the large intestine, inhibit the growth of Clostridium difficile, new research indicates. The work sheds light on the ways in which ...

PSYLLIUM FIBER PROTECTS AGAINST COLITIS VIA ACTIVATION OF BILE ACID SENSOR FXR. Cellular and Molecular Gastroenterology and Hepatology, 2023; DOI: 10.1016/j.jcmgh.2023.02.007; ...

New microbial genes responsible for bile acid conversion is a major step forward for gut health. Download PDF Copy; Reviewed. Reviewed by Emily Henderson, B.Sc. May 27 2021.

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

It sounds like bile acid in the eye would hurt, but scientists think stimulating one of its receptors can actually help protect the vision of premature newborns. Skip to content.