Establishing a neoadjuvant platform for developing targeted agents: Degarelix prior to prostatectomy for patients with intermediate- and high-risk prostate cancer. A phase I/II study of the ...

A potential new drug to treat the common cold prevents rhinoviruses and other picornaviruses from gaining a toehold in human cells, according to findings published in Nature Chemistry. Aurélie ...

Study in fission yeast revealed a key role for a set of enzymes called agmatinases, which break down the metabolite agmatine into polyamines.

In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, ...

IT has been demonstrated that pulmonary hyaline membranes in newborn infants have a basic fibrin composition that resembles a plasma clot. 1,2 The presence of fibrin in the lungs of these infants is ...

Fully automated pipeline allows for 500.000 binding energy predictions per month to speed up in silico enzyme and inhibitor screening and discovery projects GELEEN, NETHERLANDS, October 31, 2024 / ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University ...

Houston, TX – New research by investigators in Ghent, Belgium shows that intravenous treatment with MK-3402, a metallo-beta-lactamase inhibitor, can be an effective strategy in fighting antimicrobial ...