The UAB researchers showed that TREM2 — which stands for triggering receptors expressed on myeloid cells 2 — is predominantly ...

Results of an autopsy-based study revealed that sudden cardiac death and multiorgan pathology may be more closely linked to SSc than previously thought.

Fibrosis staging may also be based on other tests outside of a liver biopsy and histology. For example, a doctor may confirm liver fibrosis with a blood test that measures fibrosis 4 (Fib4) in the ...

Histology findings from paired liver biopsies showed strong improvement in fibrosis without worsening of NASH, consistent with dose-dependent reduction of all biomarkers related to fibrogenesis ...

FibroMAP combines the power of high-resolution, single-fiber, and spatially resolved datasets generated by PharmaNest's digital pathology and image analysis platform (FibroNest) with advanced ...

Liver fibrosis, a pathological condition in which the liver becomes stiff and scarred, commonly develops in the progression ...

Announcing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix ...

Data derived from: Loomba R, et al. Denifanstat, a fatty acid synthase (FASN) inhibitor, shows significant fibrosis improvement and MASH resolution in FASCINATE-2, a phase 2b 52-week international ...

"We know from histology studies that if you look at IPF lungs you'll see areas of end-stage fibrosis, but even in advanced disease, you'll see areas where the lung is relatively well preserved and ...

More information: Margaret A.T. Freeberg et al, Piezo2 Is a Key Mechanoreceptor in Lung Fibrosis that Drives Myofibroblast Differentiation, The American Journal of Pathology (2025). DOI: 10.1016/j ...

This builds on previous findings of a phase 2 trial where 59% of patients taking semaglutide saw this outcome compared with 17% taking placebo (P < .001). 3 Meanwhile, reduced liver fibrosis ...