Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...
Visualizing and quantifying DNA replication dynamics in living human cells remains challenging. Here, a new super-resolution microscopy method, 3D-SPARK, maps changes in replication nanostructures in ...
The INO80 chromatin remodelling complex has various roles in genome maintenance, acting via nucleosome sliding and H2A.Z ...
What happens when you squeeze DNA? Can pressure reveal something about how our genetic material is packed, protected, and ...
MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...
DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...
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Newly identified protein acts as a traffic controller for DNA replication
Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell ...
A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals ...
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