Understanding the delicate balance between nucleophilicity and electrophilicity is fundamental to rationalising reaction mechanisms in organic chemistry. Nucleophilic reactivity describes a molecule’s ...

In nature, the behavior of systems—whether large or small—is always governed by a few fundamental principles. For instance, ...

The current research demonstrates that this view is very fragmentary and insufficient: in reality, chemical reactions – even those studied since the 19 th century – are complex reactivity networks ...