Next, they tested whether silencing the activity of mutant-beta-catenin would affect immune cell infiltration, by using 3D tumor spheroids from two different liver cancer cells lines. This showed ...

including liver malignancies. However, the benefits are limited by multiple mechanisms of treatment resistance, including the lack of dendritic cells, which have a critical role in immune activity ...

Pancreatic cancer that spreads to the liver is especially difficult to treat because the liver naturally suppresses immune responses, creating an environment where cancer can evade detection and ...

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice.

A research team led by Prof. SUN Cheng from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, along with ...

The higher infiltration of immune cells into these tumors suggests that ... The Royal Marsden Hospital and the University of Birmingham Centre for Liver Research, UK, and Erasmus Rotterdam ...

"These findings furnish new lines of approach for therapeutic strategies that could influence immune cell infiltration in atherosclerotic plaques and could contribute in the long term to the ...

‘Small cell lung cancers do not respond well to immune checkpoint blockade therapy ... promoting neutrophil infiltration and liver damage. Human pathogenic-like Th17 cells express the chemokine ...