These factors prompted research into better and more permanent treatments for T1D. The most ... furthers the need for immune suppression to prevent the transplants from being rejected. In Deng’s ...

Type 1 diabetes is an immune ... islets, MHC molecules and TCRs? Little is understood about the function of macrophages, mast cells and various dendritic cell subsets during the pathogenesis of ...

Engineering of a novel device to treat T1D, featuring local immunosuppression and a vascularized ... caused similar amounts of vascularization and limited immune cell infiltration within the device.

Islet autoimmunity signals the first sign of self-damage of the pancreas, a hallmark of T1D," says Dr. Kim. Researchers say ...

These diseases have the same underlying manifestation – namely that the immune system is inappropriately responding to self-tissues such as the joint (RA), the kidney (SLE), the nervous system (MS) or ...

Type 1 diabetes – which affects around nine million people globally – occurs when the body’s immune system destroys insulin-producing islet cells in the pancreas. Islet transplantation has long been ...