In the healthy liver, most macrophages are classified as Kupffer cells (KCs). However, upon liver injury, as seen, for example, in obesity, another subset of macrophages called lipid-associated ...

However, it wasn't the typical liver cells that responded, but a type of immune cell called Kupffer cells that are known for ...

Research from VIB-UGent identifies lipid-associated macrophages and LAM-like Kupffer cells as critical for liver repair. The study reveals TREM2's role in clearing damaged cells and promoting recovery ...

In the healthy liver, most macrophages are classified as Kupffer cells (KCs). However, upon liver injury, as seen, for example, in obesity, another subset of macrophages called lipid-associated ...

The earliest changes in stellate cells are likely to result from paracrine stimulation by all neighboring cell types, including sinusoidal endothelium, Kupffer ... cell type in liver, are a ...

In the liver, senescence impacts key cell types including hepatocytes, liver sinusoidal endothelial cells, and Kupffer cells, and contributes to chronic liver diseases such as fibrosis ...

In 1876, Karl Wilhelm von Kupffer identified what he believed to be a single type of star-shaped cell in liver tissue. Now, immunologist Martin Guilliams from Ghent University and the VIB ...

The liver is difficult to palpate in women during ... There may be a slight increase in Kupffer cells, which contain increased amounts of periodic acid-Schiff (PAS)-positive granules.

CN Bio’s liver model recreates highly functional and metabolically active hepatic tissues. It can be maintained under ...