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LFSPRO model shows superior discrimination for Li-Fraumeni syndrome

FRIDAY, May 1, 2026 (HealthDay News) -- LFSPRO, a Mendelian, family history-based model that estimates an individual's probability of harboring a deleterious TP53 variant, shows superior ...
Medical Xpress

Novel tool more accurately predicts risk of Li-Fraumeni syndrome

In a prospective validation study, researchers at The University of Texas MD Anderson Cancer Center have demonstrated that a new mathematical model called LFSPRO was effective in supporting genetic ...
News Medical

New model improves detection of Li-Fraumeni Syndrome risk

In a prospective validation study, researchers at The University of Texas MD Anderson Cancer Center demonstrated that a new mathematical model, called LFSPRO, was effective in supporting genetic ...
ascopubs.org

Validating Risk Prediction Models for Multiple Primaries and Competing Cancer Outcomes in Families With Li-Fraumeni Syndrome Using Clinically Ascertained Data

Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease For prediction of deleterious TP53 mutations, ...