Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

The sixth annual competition showcases scientific microscopic imaging, illuminating tiny parts of nature, from individual cells to arthropods, diatoms and a zebrafish brain ...

Researchers at Peking University have developed DUET, a breakthrough dual-color miniature two-photon microscope that ...

Bioluminescence is an attractive alternative to fluorescence for live-cell imaging; however, its low intensity has prevented widespread adoption. Specialized microscopes compensate by sacrificing ...

The application of three-dimensional (3D) cell cultures such as spheroids and organoids is growing in popularity both in academia and industry. However, morphology of the 3D architecture remains ...

A new hybrid microscope for the first time allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. (Nanowerk ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a ...

Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of the most detailed views of life ever recorded. Day and night, they collect ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

The polarized diSPIM microscope, which can image full 3D orientation and position of molecules in cells. The instrument was constructed in the Hari Shroff lab at the National Institute of Biomedical ...