When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an ...

Researchers have identified an enzyme that controls the maturation and long-term survival of tissue-resident macrophages.

In regenerative medicine, macrophages and stem cells play pivotal roles in repairing central nervous system (CNS) injuries. These cells are instrumental due ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...

Acute-on-chronic liver failure (ACLF) is a life-threatening syndrome characterized by systemic inflammation and immune dysregulation, in which ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...