Although the mechanisms by which anesthetic drugs induce the state of general anesthesia have been considered one of the biggest mysteries of modern medicine and science, new research is deciphering ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

It's World Anesthesia Day tomorrow! So, we invite you to take a deep breathe. Picture a relaxing scene. Maybe a beach in ...

The application of general anesthesia in clinical therapy has been an indispensable part of modern medicine for more than a century. However, due to the complexity of the brain and the extensive ...

Although general anesthetics are often said to be nonspecific agents, it is likely that they act at a much more restricted set of target sites than commonly believed. The traditional view has been ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

An impressive new study, led by scientists from the Boston Children's Hospital, has developed a novel method to tame one of the world's most potent toxins, tetrodotoxin, commonly found in the ...

In a paper recently published in Neuron, researchers from the group of Botond Roska at IOB reveal how different cell types in cortex change their activity during general anesthesia, helping to ...

General anesthetics induce a coma-like state within seconds, allowing patients to be operated on without feeling pain or discomfort. Yet very little is known about how these drugs work. Now research ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...