In regenerative medicine, macrophages and stem cells play pivotal roles in repairing central nervous system (CNS) injuries. These cells are instrumental due ...

A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell ...

Instead, they found a mechanism that speeds muscle repair, which may inspire new medicines for slowing muscle wasting and helping injured people. The study also suggests that macrophages could ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Sepsis is a fatal syndrome characterized by life-threatening organ dysfunction originating from a chaotic and unchecked innate immune response to infection. Notably, macrophages are the master ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer ...

Macrophages are white blood cells that play a key role in helping to protect us against microscopic threats, from infections to cancer. These cells constantly survey the body’s tissues and consume ...

This work illuminates the essential role of epithelial ATG5 in defending against P. aeruginosa. Atg5 deficiency impairs bacterial clearance and aggravates inflammation via inflammasome activation, and ...