Invariant natural killer T (iNKT) cells represent a unique lymphocyte subset that bridges innate and adaptive immunity. Their development originates in the thymus from double‐positive precursor cells, ...
Cancer immunotherapy has been transformed by engineered T cells, but those bespoke treatments are slow, expensive, and out of reach for many patients who need help quickly. A new way to generate vast ...
Natural killer (NK) cells are the bodyguards of our immune system. As a first line of defense, they destroy invading pathogens, foreign bodies, and infected cells in early stages, thereby preventing ...
Safety and efficacy of HLA-G–targeted CAR T cells (IVS-3001) in patients with advanced HLA-G–positive solid tumors: Clinical trial in progress. This is an ASCO Meeting Abstract from the 2025 ASCO ...
A multi-omics atlas reveals how centenarians maintain potent cytotoxic NK and T cell circuits, offering clues to designing therapies that counteract immune decline with age. Study: A comprehensive ...
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Engineered CAR-NK cells could evade immune rejection and target cancer more effectively
One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be ...
First Phase 2 chemotherapy-free, lymphodepletion-free, off-the-shelf CAR-NK cell therapy plus ANKTIVA® and rituximab regimen ...
Your immune system is your body’s built-in defense network, working nonstop to protect you from bacteria, viruses, and other ...
As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, making people more susceptible to a variety of infections. To try to ...
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