Researchers have developed a novel technique that allows them to dial up or tone down the amount of a certain metastatic protein inhibitor (BACH1) within a cell. This could provide a new path in ...

July 13, 2010 (Los Angeles, California) — An investigational compound that acts as a heat shock protein (HSP) inhibitor has shown promise in the treatment of lung cancer and in many other malignancies ...

When many cancers advance, spread and reoccur, checkpoint inhibitors can help keep difficult tumors at bay. These antibody-based immunotherapies can restore the body’s ability to recognize and ...

The health impacts of a complex protein that plays a major role in the development of Alzheimer's disease and heart conditions can be lessened by three kinds of drug inhibitors, according to ...

Researchers have identified a new way to make opioids safer, increasing the pain-relieving properties of opioids while decreasing unwanted side effects through the spinal inhibition of a Heat shock ...

Several neurodegenerative diseases begin when toxic protein clumps form in neurons. Scientists have yet to find a good way to clear these clumps from cells. Researchers now report that a ...

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

--First data disclosure from Ribometrix’s RNA-targeting drug discovery platform identifies small molecules targeting c-MYC, a validated but historically undruggable cancer driver -- --Data shows ...

The oral respiratory syncytial virus (RSV) fusion protein inhibitor AK0529 was found to be well tolerated and reduced viral load in infants. Both viral load and Wang Respiratory Scores improved after ...

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could prevent ...