SNP genotyping that was based on traditional PCR was prohibitively expensive for large-scale genome studies. Our technology allows the traditional PCR to be used in SNP genotyping in a high-throughput ...

β-Globin gene mutations reduce or terminate the production of beta globin chains, of which approximately 10% are large deletions within the β-globin gene cluster. Because gene deletion leads to loss ...

Short Tandem Repeat (STR-) and Single Nucleotide Polymorphism (SNP-) genotyping have been extensively studied within forensic kinship analysis. Nevertheless, no results have been reported on kinship ...

SNP chips, a type of DNA microarray frequently employed by consumer genomics companies, are "extremely unreliable" when identifying clinically-relevant variants that are rare among the general ...

High-throughput single nucleotide polymorphism (SNP) arrays are important genotyping tools that accelerate breeding programs and basic research. In the cultivation wax gourd, a vital vegetable crop in ...

Single nucleotide polymorphisms (SNPs) are pouring into public databases, but methods for analyzing large numbers of SNPs in population studies lag behind. In the January 16 Proceedings of the ...

Refined Tools for Real-Time Single Particle Tracing and Dissection of Signaling Pathways Nanotechnology is the creation and utilization of materials, devices, and systems through the control of matter ...