Splenomegaly is one of the characteristic signs of an overactive spleen. It can cause platelets to pool inside of your spleen and cause thrombocytopenia. Thrombocytopenia is when you have a low ...

Jakafi led to improved symptom score and spleen volume reductions in patients with myelofibrosis, regardless of anemia or transfusion status, recent research showed. Patients with myelofibrosis who ...

Please provide your email address to receive an email when new articles are posted on . The combination of pelabresib plus ruxolitinib significantly increased the proportion of patients with ...

Cricketer Shreyas Iyer's recent spleen injury highlights the dangers of splenic rupture in high-impact sports. A blow or fall can cause this delicate organ to tear, leading to internal bleeding with ...

Patients with myelofibrosis (MF) who achieved a spleen response while taking ruxolitinib and lost it had survival outcomes similar to patients who did not respond, according to results from a ...

Findings of MANIFEST-2 show “valuable evidence that the addition of pelabresib offers meaningful improvements over JAK inhibitor monotherapy as a first-line approach for patients with myelofibrosis,” ...