The inflammasome is a multiprotein intracellular complex that detects pathogenic microorganisms and sterile stressors, and that activates the highly pro-inflammatory cytokines interleukin-1b (IL ...
"Buprenorphine is essentially triggering sterile inflammation through this innate immune receptor that classically recognizes infections," Abrahams says. The NLRP3 inflammasome is a protein ...
NodThera is developing a portfolio of novel, potent and selective NLRP3 inflammasome ... inflammatory mechanisms orchestrated by the innate immune system to fend off pathogens and other sterile ...
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