It is a common perception that approximately 50% of heart failure (HF) patients present with a normal or near-normal left ventricular (LV) ejection fraction ("HF with preserved systolic function"), ...

Patients with either systolic (HFrEF) or diastolic (HFpEF) heart failure usually present in the same way. Common signs and symptoms include the following: worsening fatigue; dyspnea on exertion, which ...

Blood pressure consists of two numbers. Systolic pressure, the force exerted on blood vessels when the heart beats, is the upper number. Diastolic pressure, the force exerted when the heart is at rest ...

Hierarchical composite endpoints for heart failure trials - answering the question: What fraction of the composite endpoint is due to cardiovascular mortality, hospitalization, or quality of life?

Michael Gotthardt at the Max Delbrück Center and collaborators are developing a drug to treat a common type of heart failure ...

ORLANDO, FLA. – In the first such analysis of the costs of heart failure, Duke University Medical Center researchers have found that elderly patients with the debilitating heart disorder have health ...

High output and low output heart failure refer to how much blood your heart pumps to your body with each heartbeat. In both cases, the output is not enough to meet your body’s needs. A diagnosis of ...

Symptoms of left-sided heart failure can include chest pain, fatigue, shortness of breath, and leg swelling. They can be similar to other medical conditions and, early on, even go unnoticed. When the ...

The SGLT2 inhibitor medicines have changed how heart failure is managed. Originally sodium-glucose cotransporter 2 (SGLT2) inhibitors were used to lower blood sugar levels in people who have type 2 ...

Each month, The Clinical Advisor makes one new clinical feature available ahead of print. Don’t forget to take the poll. The results will be published in the next month’s issue. The American Heart ...