Pin1 regulates a subset of phosphoproteins by isomerizing phospho-Ser/Thr-Pro motifs via a ‘post-phosphorylation’ mechanism. Here, we characterize TR3 as a novel Pin1 substrate, and the mitogenic ...

Autophagy is linked to cell death, yet the associated mechanisms are largely undercharacterized. We discovered that melanoma, which is generally resistant to drug-induced apoptosis, can undergo ...