Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

Circadian rhythms are the daily fluctuations in physiological processes that govern cell cycles and timing of behaviors.

Scientists have discovered a novel subset of cancer-fighting immune ... and Tumor Microenvironment Center at UPMC Hillman. "By better understanding different types of B cells and their location ...

Other cancer immunotherapies include vaccines and T cell infusions. A combinatorial therapeutic strategy that modulates several gene targets within the tumor microenvironment through a CRISPR ...

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which ...

Scientists have made an important discovery about the relationship between hematopoietic stem cells (HSCs) and immune response evasion. Their findings show how certain HSCs have regulatory functions ...

Inside the microenvironment of the original tumor, the immune system is suppressed so is less able to kill cancer cells. However, once these lone cancer cells migrate, the immune system can target ...