Epstein-Barr virus infection induces the upregulation of glycolysis in intestinal macrophages, which subsequently activates Gasdermin D, NLRP3, interleukin-1β, and interleukin-18 in macrophages within ...

A microglia replacement approach demonstrates that brain macrophages with patient mutations from Aicardi–Goutières syndrome, a genetic, brain predominant interferonopathy, are sufficient to drive ...