Mutations in a gene linked to Crohn's disease deprive vital immune cells of their capacity to change modes, which leads to overreaction and inflammation, a recent study has found, per ScienceAlert.

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes. This, in turn, has led to an increase in peripheral neuropathy—nerve damage, ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...

In regenerative medicine, macrophages and stem cells play pivotal roles in repairing central nervous system (CNS) injuries. These cells are instrumental due ...

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues ...

Risk assessment is complicated, and not the same for all groups. Participants in the Dominantly Inherited Alzheimer Network carry AD mutations that spur massive plaque deposition and lead to memory ...

Trojan horse” approach may enable ‘antigen-independent’ therapy with potential to treat cancers not traditionally amenable to immunotherapy.