Mutations in a gene linked to Crohn's disease deprive vital immune cells of their capacity to change modes, which leads to overreaction and inflammation, a recent study has found, per ScienceAlert.

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

In regenerative medicine, macrophages and stem cells play pivotal roles in repairing central nervous system (CNS) injuries. These cells are instrumental due ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer. Chief among this force is the macrophage, a white blood cell that surveils tissues ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes. This, in turn, has led to an increase in peripheral neuropathy—nerve damage, ...

In the 1980s, when Stella Kourembanas, MD, began her career in neonatology, she cared for newborns with pulmonary hypertension, a disease that results in abnormally high blood pressure in the lung ...

Cancer specialists have long known that anemia, caused by a lack of healthy red blood cells, can arise when cancer metastasizes to the bone, but it’s been unclear why. A research team led by Princeton ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an ...