Powerball winning numbers for Wed., Oct. 22, 2025
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The winning numbers have been drawn for Tuesday night's Mega Millions jackpot worth estimated at $650 million ($304.1 million cash).
After no grand prize winner from the Oct. 17 drawing, the Mega Millions jackpot for Oct. 21 is up to $650 million with a cash value of $304.1 million.
CLEVELAND, Ohio — The Wednesday, Oct. 22, 2025, Powerball drawing has selected the winning numbers for a jackpot estimated at $320 million. The numbers are 18-37-52-54-60 Powerball 12 Power Play 2x. The Classic Lotto numbers are 4-11-24-25-26-28 Kicker 301195. The jackpot is $9.6 million for the Saturday, Oct. 25 drawing.