A new study by researchers from Taiwan and the US suggests that the removal of unnecessary glycans from spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposes ...

Close collaboration between academic and industrial groups is vital to ensuring glycosylation models are fit for deployment. Good Studio/Stock.Adobe.com Many of the highest-grossing protein ...

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most ...

Protein N-glycosylation is a ubiquitous and critical post-translational modification in eukaryotic cells, whereby oligosaccharides are covalently attached to asparagine residues within polypeptides.

Glycosylation modeling is a useful tool for determining biopharma product quality, and establishing collaboration between academic and industrial groups ensures that such modeling tools are fit for ...

Proteins in higher organisms, from fruit flies to humans, which are secreted or displayed on cell surfaces must have sugars attached to them in order to function properly. This glycosylation process ...

A research team has successfully identified and produced the first recombinant mucin protein derived from the Edible-nest Swiftlet Aerodramus fuciphagus (AfMuc). The study provides insights into the ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Mapping of the gene network that ...

This is a preview. Log in through your library . Abstract The process termed "epithelial-mesenchymal transition" (EMT) was originally discovered in ontogenic development and has been shown to be one ...

Glycans can enhance, dampen or redirect protein activity. Glycan modification can alter size, charge and geometry, shield an enzyme from degradation, help a hormone find its receptor or steer an ...

An international team of scientists has discovered the gene mutation responsible for a condition in which eye and brain development is severely disrupted in affected infants. An international team of ...