Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

Biohub today announced the release of a world model of protein biology: a scientific engine for prediction, design, and ...

The deep sea is a unique "evolutionary engine," with one of the richest and most unexplored sources of genetic diversity on ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics. Many ...

Non-profit research organisation Biohub has released what it claims is an AI-powered "world model" of protein biology that can drive the prediction, design, and discovery of new therapies. The ...

This Brush Up is sponsored by Quanterix. Learn more about tau biomarkers and clinical applications. Tau is a flexible protein that stabilizes the internal structure of neurons and supports ...

RNA therapeutics have emerged as one of the most promising new classes of medicines. Eight small interfering RNA (siRNA) ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...

Proteins systematically lose their protective hydration shell when their environment becomes more acidic. Until recently, ...