Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy.

Researchers discover that bone marrow cancer cells diversify drastically when exiting the bone marrow, which also affects the ...

Penn researchers have developed a platform that emulates human bone marrow’s native environment. This breakthrough addresses a critical need in medical science, as animal studies often fail to fully ...

When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response in the region changes, researchers report. The detailed insights into cancer ...

When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response ...

Many immune checkpoint blockade drugs keep cancer cells from evading ... 1 But NK cells did not efficiently penetrate the bone marrow, which as the source of AML cells, was a prime target for lasting ...

A research team from Columbia Engineering and the Irving Institute for Cancer Dynamics achieved a significant finding in cancer immunotherapy.The team discovered a unique population of immune cells ...

The team identified that a key cell type in the DLI product and features of the tumor microenvironment in ... only the range of cell types in the bone marrow, but also how those cells were interacting ...

However, treatments preventing their release from bone marrow may help reduce the exaggerated immune response that contributes to poor outcomes in patients with severe COVID-19. Our work once again ...