When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response in the region changes, researchers report. The detailed insights into cancer ...
Cancer models developed with 3D bioprinting technology allow for rapid evaluation of individual drug responses.
Researchers discover that bone marrow cancer cells diversify drastically when exiting the bone marrow, which also affects the ...
When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response ...
Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...
One of the most significant challenges in cancer treatment is the development of drug resistance by cancer cells, which often ...
Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy.
Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.
Scientists have progressed from merely provoking an anti-cancer immune response to designing it ...
Emerging research suggests that the bone marrow microenvironment, or marrow niche, plays a critical role in both immune system regulation and disease progression. The bone marrow niche is essential ...