FGF19 negatively regulates bile acid synthesis and recombinant FGF19 increases the metabolic rate of mice. Unfortunately, FGF19 transgenic mice develop hepatocellular carcinomas, and this side ...

Fatty acids are organic acids with at least one carboxyl (-C(=O)OH, -COOH or -CO2H) group and a long carbon chain that can be joined by double bonds, as in unsaturated fatty acids, or single bonds ...

Bile acids of serum, fecal samples from human and mice were analysised. Body weight, average feed intake, blood glucose, insulin levels and oral glucose tolerance test was performed among each groups.

Salk Institute researchers found that regulating bile acids—specifically reducing harmful ones and increasing UDCA—can enhance T cell function and potentially make immunotherapy more effective for ...

Red yeast rice has been used as an alternative to statins in statin-intolerant patients. The bile acid sequestrants can reduce LDL-C by 10–20% when used as monotherapy. The addition of niacin to ...