Uric acid is a waste product found in urine. If your body makes too much or doesn't eliminate enough of it, uric acid levels can become too high—a condition known as hyperuricemia. High uric acid ...

FGF19 negatively regulates bile acid synthesis and recombinant FGF19 increases the metabolic rate of mice. Unfortunately, FGF19 transgenic mice develop hepatocellular carcinomas, and this side ...

Fatty acids are organic acids with at least one carboxyl (-C(=O)OH, -COOH or -CO2H) group and a long carbon chain that can be joined by double bonds, as in unsaturated fatty acids, or single bonds ...

Bile acids of serum, fecal samples from human and mice were analysised. Body weight, average feed intake, blood glucose, insulin levels and oral glucose tolerance test was performed among each groups.

Malic acid benefits can include acne treatment, and skin care such as exfoliation and hydration. It is an alpha hydroxy acid, found naturally in fruits and wines and used as an ingredient in ...

Salk Institute researchers found that regulating bile acids—specifically reducing harmful ones and increasing UDCA—can enhance T cell function and potentially make immunotherapy more effective for ...

All procedures carried out in this experiment were reviewed and approved by the Animal Protocol Review Committee of the University of Agriculture, Faisalabad. The experiment was conducted at the ...

Red yeast rice has been used as an alternative to statins in statin-intolerant patients. The bile acid sequestrants can reduce LDL-C by 10–20% when used as monotherapy. The addition of niacin to ...

While studying mouse and human liver tumors, they discovered that certain bile acids in the liver could affect the activity of cancer-fighting immune cells, called T cells. The researchers ...

Bile acids (BAs) and incretins are gut hormones involved in digestion and absorption of fatty acids, and insulin secretion, respectively. In recent years BAs and incretins are increasingly recognized ...