Central to these discussions is the role of the pituitary-targeted gland axes (PTGA) in regulating hepatic lipid metabolism.

and fibrosis in a model of NAFLD induced by feeding mice a high-fat and high-cholesterol diet. Further analysis showed that Asah1 deficiency increased harmful lipids accumulation, disrupted lipid ...

Discover preclinical studies that indicate that empagliflozin reduces liver fat, improves liver function markers, and ...

Ready to save your liver? Transcription factors are paving the way for metabolic dysfunction-associated fatty liver disease ...

Nonalcoholic fatty liver disease (NAFLD ... modest wine drinking might not confer sufficient benefits in cardiovascular or lipid profile to justify any potential risk of worsening the underlying ...

Metabolic-dysfunction-associated steatotic liver disease (MASLD) arises from excessive intrahepatic triglyceride accumulation ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions ...

Her research team has a focus on lipid lipoprotein metabolism in health and metabolic disorders including diabetes, dyslipidemias, and NAFLD.

This study shows that the SAAR diet regulates glucose and lipid metabolism to support weight control without impacting ...

Therefore, understanding how NAFLD progresses to fibrotic NASH is ... increased harmful lipids accumulation, disrupted lipid metabolism, triggered cellular stress, and impaired the cell's waste ...

Impaired lysosomal function (breaking down waste) leads to accumulation of excess lipids in liver cells, worsening NAFLD and contributing to its progression. By analyzing a clinical gene-profiling ...