Fatty Acid Metabolism Disruption: In NAFLD, abnormal fatty acid metabolism in the liver contributes to lipid dysregulation, leading to an increase in circulating free fatty acids.

International Journal of Obesity - Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD Skip to main content Thank you ...

Given that dysfunctional hepatic lipid metabolism is a central feature of these disease states, and that reducing lipid burden in the liver is associated with improvements in NAFLD and insulin ...

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GLP-1 drugs currently being tested in China target complications associated with obesity such as heart disease, fatty liver ...

Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer. To enhance preventive and ...

image: A new Chinese Medical Journal review assesses the role of bile acids and lipid metabolism dysregulation in the progression of non-alcoholic fatty liver disease. view more Credit: Prof ...

The gene Asah1 plays a crucial role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) to more severe forms by regulating lipid homeostasis and cellular maintenance.

Further analysis showed that Asah1 deficiency increased harmful lipids accumulation, disrupted lipid metabolism, triggered cellular stress, and impaired the cell's waste disposal system.

Understanding the link between Non-Alcoholic Fatty Liver Disease (NAFLD) and cardiovascular disease is essential. ... The liver plays a central role in lipid and cholesterol metabolism.